Description

5-Methyl-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-purity, versatile boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	5-Methyl-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1116093-68-5
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	2-Cyano-4-methylphenylboronic acid pinacol ester; (2-Cyano-4-methylphenyl)boronic acid pinacol ester; 5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylbenzonitrile; Pinacol (2-cyano-4-methylphenyl)boronate; CAS 1116093-68-5
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. Each lot is subjected to comprehensive analytical testing, including NMR, HPLC, and GC analysis, to verify identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.