Description

6-Bromo-3-Chloro-2-Fluorobenzaldehyde is a high-purity, multi-halogenated benzaldehyde derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the halogen atoms for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromo and chloro substituents.
• Fluorine Chemistry: The fluorine atom provides metabolic stability, making this aldehyde valuable for medicinal chemistry programs focused on improving drug candidate profiles.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6-Bromo-3-Chloro-2-Fluorobenzaldehyde
CAS No.	1114809-02-7
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	2-Fluoro-6-bromo-3-chlorobenzaldehyde; 3-Chloro-2-fluoro-6-bromobenzaldehyde; 6-Bromo-3-chloro-2-fluorobenzenecarboxaldehyde; Benzaldehyde, 6-bromo-3-chloro-2-fluoro-; (6-Bromo-3-chloro-2-fluorophenyl)methanone (tautomer); 2-Bromo-5-chloro-6-formyl-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.