Description

2-Amino-4-Chloro-5-Hydroxybenzoic Acid Methyl Ester Hydrochloride is a high-purity, synthetically derived organic salt serving as a critical building block in advanced pharmaceutical and agrochemical research. Its value lies in its multifunctional chemical structure, which provides a versatile scaffold for synthesizing novel active compounds, particularly in the development of targeted small-molecule drugs. This intermediate is essential for R&D chemists and process development scientists working in medicinal chemistry, where it is used to create potential candidates for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for specialized therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological pathways and mechanisms.
• Fine Chemical Production: Employed in multi-step synthetic routes for producing other high-value, specialized fine chemicals.

Basic Information

Product Name	2-Amino-4-Chloro-5-Hydroxybenzoic Acid Methyl Ester Hydrochloride
CAS No.	1113049-83-4
Molecular Formula	C9H9Cl2NO3
Molecular Weight	250.08 g/mol
Synonyms	Methyl 2-Amino-4-Chloro-5-Hydroxybenzoate Hydrochloride; Benzoic acid, 2-amino-4-chloro-5-hydroxy-, methyl ester, hydrochloride; Methyl 5-Hydroxy-2-amino-4-chlorobenzoate HCl; 2-Amino-4-chloro-5-hydroxy-methylbenzoate hydrochloride; 4-Chloro-5-hydroxyanthranilic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-5-Hydroxybenzoic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.