Description

Potassium Isoquinoline-4-Trifluoroborate is an organotrifluoroborate salt, a versatile and stable building block in modern synthetic chemistry. Its primary value lies in its exceptional utility as a coupling partner in transition metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex heterocyclic systems. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-yielding synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor for constructing isoquinoline-containing active pharmaceutical ingredients (APIs) and drug candidates via cross-coupling methodologies.
• Agrochemical Research & Development: Used in the synthesis of novel heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science & Organic Electronics: Serves as a building block for creating organic semiconductors, light-emitting materials, and other functional molecules requiring the isoquinoline scaffold.
• Catalysis & Ligand Development: Employed in the preparation of novel ligands and catalysts where the isoquinoline moiety modulates metal center properties.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating fluorescent probes for imaging and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and exploring new chemical space.

Basic Information

Product Name	Potassium Isoquinoline-4-Trifluoroborate
CAS No.	1111733-07-3
Molecular Formula	C9H6BF3KN
Molecular Weight	229.06 g/mol
Synonyms	Potassium (Isoquinolin-4-yl)trifluoroborate; 4-(Trifluoroborato)isoquinoline Potassium Salt; Isoquinoline-4-trifluoroboronic Acid Potassium Salt; Potassium 4-Isoquinolyltrifluoroborate; 4-Isoquinolineboronic Acid, Trifluoro-, Potassium Salt; Potassium Isoquinolin-4-yltrifluoroboranuide; K-4-IQTFB
EINECS	Contact for details

Quality Control

Our Potassium Isoquinoline-4-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B), HPLC for purity assessment, and KF titration for moisture content, to ensure compliance with stringent specifications. Comprehensive Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) in a glovebox or using appropriate Schlenk techniques to prevent decomposition. For long-term stability, consider storage in a freezer (-20°C) under inert conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (1H)	≥ 95.0%
Solubility	Soluble in DMF, DMSO; partially soluble in MeOH, Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.