Description

Potassium 5-Indolyltrifluoroborate is a versatile organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity, serving as a superior alternative to traditional boronic acids in Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the efficient synthesis of complex indole-containing molecules for drug discovery and advanced material development.

Application

• Pharmaceutical Intermediates: A key reagent for constructing indole scaffolds in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides containing indole motifs.
• Material Science: Employed in the synthesis of organic electronic materials, ligands for catalysis, and advanced polymers.
• Cross-Coupling Reactions: A stable and air-tolerant partner for palladium-catalyzed Suzuki-Miyaura couplings, facilitating carbon-carbon bond formation.
• Chemical Biology & Proteomics: Useful as a bioconjugation handle or in the synthesis of molecular probes and tags.
• Academic & Industrial R&D: A fundamental tool for synthetic organic chemists exploring new reaction methodologies and complex molecule synthesis.

Basic Information

Product Name	Potassium 5-Indolyltrifluoroborate
CAS No.	1111733-03-9
Molecular Formula	C8H6BF3KN
Molecular Weight	220.05 g/mol
Synonyms	Potassium (1H-Indol-5-yl)trifluoroborate; 5-Indolyltrifluoroborate Potassium Salt; Potassium 5-Indoleboronate(1-), Trifluoro-; 1H-Indole-5-boronic Acid, Trifluoroborate Potassium Salt; 5-(Potassiumtrifluoroboranyl)-1H-indole; Potassium 1H-Indol-5-yltrifluoroboranuide; 5-Indolyl-BF3K; Potassium Trifluoro(1H-indol-5-yl)borate
EINECS	Contact for details

Quality Control

Our Potassium 5-Indolyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F), HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
¹H NMR	Conforms to structure
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.