Description

Potassium 2-Methoxypyrimidine-5-Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. This compound is valued for its role in facilitating efficient cross-coupling reactions, enabling the construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, essential for constructing biaryl and heteroaryl structures.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyrimidine cores for therapeutic applications.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Materials Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of molecular probes and tool compounds for target identification and validation.
• Process Chemistry & Scale-up: Provides a stable, crystalline, and often safer-to-handle alternative to boronic acids in large-scale manufacturing processes.

Basic Information

Product Name	Potassium 2-Methoxypyrimidine-5-Trifluoroborate
CAS No.	1111732-99-0
Molecular Formula	C5H5BF3KN2O
Molecular Weight	216.01 g/mol
Synonyms	Potassium (2-Methoxypyrimidin-5-yl)trifluoroborate; 2-Methoxypyrimidine-5-trifluoroborate Potassium Salt; 5-(Trifluoroborato)-2-methoxypyrimidine Potassium Salt; Potassium 2-Methoxypyrimidin-5-yltrifluoroborate; 2-Methoxy-5-pyrimidyltrifluoroborate Potassium Salt; Potassium Trifluoro(2-methoxypyrimidin-5-yl)borate
EINECS	Contact for details

Quality Control

Our Potassium 2-Methoxypyrimidine-5-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.