Description

Potassium 2,4-Dimethoxypyrimidine-5-Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates containing pyrimidine scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyrimidine-based structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and other specialty chemicals.
• Suzuki-Miyaura Cross-Coupling: Functions as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation.
• Chemical Library Development: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable, robust synthetic routes for commercial manufacturing.

Basic Information

Product Name	Potassium 2,4-Dimethoxypyrimidine-5-Trifluoroborate
CAS No.	1111732-97-8
Molecular Formula	C6H7BF3KN2O2
Molecular Weight	230.04 g/mol
Synonyms	Potassium (2,4-Dimethoxypyrimidin-5-yl)trifluoroborate; 2,4-Dimethoxypyrimidine-5-trifluoroborate Potassium Salt; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4-dimethoxypyrimidine (protected form precursor); Potassium 2,4-Dimethoxy-5-pyrimidyltrifluoroborate; 5-Trifluoroboratomethyl-2,4-dimethoxypyrimidine Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 2,4-Dimethoxypyrimidine-5-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full analytical data are provided for every shipment to guarantee consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term stability and to prevent decomposition. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
19F NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.