Description

Potassium Trifluoro(6-Fluoropyridin-3-Yl)Borate is a high-purity organoboron reagent, specifically a potassium trifluoroborate salt. This compound is a valuable and stable synthetic building block, prized for its compatibility with Suzuki-Miyaura cross-coupling reactions under mild conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex fluorinated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing fluoropyridine motifs, enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the 6-fluoropyridin-3-yl group is a critical pharmacophore.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronic acid surrogate for palladium-catalyzed C-C bond formation with aryl/heteroaryl halides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, requiring precise fluorinated aromatic structures.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules with fluorinated tags for imaging and diagnostic applications.

Basic Information

Product Name	Potassium Trifluoro(6-Fluoropyridin-3-Yl)Borate
CAS No.	1111732-94-5
Molecular Formula	C5H3BF4KN
Molecular Weight	210.99 g/mol
Synonyms	Potassium (6-Fluoropyridin-3-yl)trifluoroborate; 3-Pyridineboronic acid, 6-fluoro-, potassium trifluoroborate salt; (6-Fluoro-3-pyridinyl)trifluoroborate potassium salt; Potassium 6-fluoropyridin-3-yltrifluoroborate; 6-Fluoropyridin-3-yltrifluoroboronic acid potassium salt; Potassium Trifluoro(6-fluoropyridin-3-yl)borate(1-); K-6-Fluoropyridyl-3-trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(6-Fluoropyridin-3-Yl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.