Description

Potassium 3,5-Dimethylisoxazole-4-Yltrifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is critical for constructing complex molecular architectures. This reagent is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking reliable and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those containing the isoxazole heterocycle.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boronic acid surrogate for palladium-catalyzed carbon-carbon bond formation.
• Materials Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and functional polymers.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating chemical probes for biological target identification.
• Scale-up Process Chemistry: Its stability makes it suitable for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing.

Basic Information

Product Name	Potassium 3,5-Dimethylisoxazole-4-Yltrifluoroborate
CAS No.	1111732-84-3
Molecular Formula	C5H6BF3KNO
Molecular Weight	209.01 g/mol
Synonyms	Potassium (3,5-Dimethyl-4-isoxazolyl)trifluoroborate; 3,5-Dimethylisoxazole-4-trifluoroborate Potassium Salt; 4-Trifluoroborato-3,5-dimethylisoxazole Potassium Salt; Potassium 3,5-Dimethyl-1,2-oxazol-4-yltrifluoroboranuide; (3,5-Dimethylisoxazol-4-yl)trifluoroborate Potassium; Potassium (3,5-Dimethylisoxazol-4-yl)trifluoroborate; K-3,5-Dimethylisoxazole-4-trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 3,5-Dimethylisoxazole-4-Yltrifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.