Description

Potassium 4-Methylthiophene-2-Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl and heteroaryl structures. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it facilitates the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex heterocyclic cores and biaryl motifs present in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific thiophene-based architectures.
• Material Science & Organic Electronics: Serves as a precursor for creating conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Useful for incorporating the 4-methylthiophene moiety into molecular probes and bio-conjugates for imaging and diagnostic applications.
• Scalable Process Chemistry: Its stability makes it suitable for optimization and scale-up in kilo-lab and pilot plant environments for commercial production.

Basic Information

Product Name	Potassium 4-Methylthiophene-2-Trifluoroborate
CAS No.	1111732-75-2
Molecular Formula	C5H5BF3KSS
Molecular Weight	215.07 g/mol
Synonyms	Potassium (4-Methylthiophen-2-yl)trifluoroborate; 4-Methylthiophene-2-trifluoroborate Potassium Salt; Potassium 4-Methyl-2-thienyltrifluoroborate; 2-(4-Methylthienyl)potassium trifluoroborate; 4-Methyl-2-thienyltrifluoroboronic acid potassium salt; Potassium 4-Methyl-2-thienyltrifluoroboronate
EINECS	Contact for details

Quality Control

Our Potassium 4-Methylthiophene-2-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term stability and to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.