Description

3-Chloro-7-Azaindole-5-Boronic Acid Pinacol Ester is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling efficient cross-coupling reactions like Suzuki-Miyaura to construct complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating targeted small molecule libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active heterocyclic compounds.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronic ester group facilitates efficient palladium-catalyzed C-C bond formation with aryl/heteroaryl halides.
• Medicinal Chemistry & Drug Discovery: Enables rapid parallel synthesis and structure-activity relationship (SAR) studies for lead optimization.
• Contract Research & Manufacturing (CRO/CMO): Supplied as a high-purity standard for custom synthesis and scale-up projects.

Basic Information

Product Name	3-Chloro-7-Azaindole-5-Boronic Acid Pinacol Ester
CAS No.	1111638-73-3
Molecular Formula	C13H14BClN2O2
Molecular Weight	276.52 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-5-boronic acid pinacol ester; 3-Chloro-7-azaindole-5-boronic acid pinacol ester; 3-Chloro-5-borono-1H-pyrrolo[2,3-b]pyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Chloro-7-Azaindole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.