Description

Imidazo[1,2-A]Pyrimidine, 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, especially in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
• Material Science: Precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Research: Enables the construction of complex imidazopyrimidine-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Imidazo[1,2-A]Pyrimidine, 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1111638-06-2
Molecular Formula	C13H20BN3O2
Molecular Weight	261.13 g/mol
Synonyms	2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyrimidine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylimidazo[1,2-a]pyrimidine; 2-Methylimidazo[1,2-a]pyrimidine-6-boronic acid pinacol ester; Imidazo[1,2-a]pyrimidine-6-boronic acid, 2-methyl-, pinacol ester; 1111638-06-2; 2-Methyl-6-(pinacolboranyl)imidazo[1,2-a]pyrimidine
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyrimidine boronic ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance in cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.