Description

1-(5-Bromo-2-Fluoropyridin-3-Yl)Ethanone is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for further functional group transformations in medicinal chemistry.
• Life Science Reagents: Employed in the design and synthesis of biochemical probes, fluorescent tags, and molecular tools for diagnostic and research applications.

Basic Information

Product Name	1-(5-Bromo-2-Fluoropyridin-3-Yl)Ethanone
CAS No.	1111637-74-1
Molecular Formula	C7H5BrFNO
Molecular Weight	218.02 g/mol
Synonyms	1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one; 3-Acetyl-5-bromo-2-fluoropyridine; 5-Bromo-2-fluoro-3-acetylpyridine; Ethanone, 1-(5-bromo-2-fluoro-3-pyridinyl)-; 5-Bromo-2-fluoronicotinoyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-2-Fluoropyridin-3-Yl)Ethanone adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. All batches are characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.