Description

2-(5-Bromofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a furan-containing boronic ester, widely used in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via cross-coupling reactions, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create complex heterocyclic compounds found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for developing organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and target engagement.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	2-(5-Bromofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1111096-25-3
Molecular Formula	C₁₀H₁₄BBrO₃
Molecular Weight	273.93 g/mol
Synonyms	5-Bromo-2-furanboronic acid pinacol ester; 2-(5-Bromo-2-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Bromofuran-2-yl)boronic acid pinacol ester; 5-Bromo-2-furylboronic acid pinacol ester; 5-Bromofuran-2-ylboronic acid pinacol ester; Pinacol (5-bromofuran-2-yl)boronate; 5-Bromo-2-furanylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(5-Bromofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.