Description

5-Bromo-4-Methylthiophene-2-Boronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis for constructing complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing thiophene-containing drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Serves as a precursor for organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Research: Enables the synthesis of complex, functionalized thiophene derivatives for academic and industrial R&D programs.
• Ligand & Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for transition metal-mediated reactions.

Basic Information

Product Name	5-Bromo-4-Methylthiophene-2-Boronic Acid, Pinacol Ester
CAS No.	1111095-99-8
Molecular Formula	C11H16BBrO2S
Molecular Weight	303.02 g/mol
Synonyms	5-Bromo-4-methylthiophene-2-boronic acid pinacol ester; 2-(5-Bromo-4-methylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Bromo-4-methyl-2-thienylboronic acid pinacol ester; (5-Bromo-4-methylthiophen-2-yl)boronic acid pinacol ester; 5-Bromo-4-methylthiophene-2-boronic acid neopentyl glycol ester (common alternative); B-(5-Bromo-4-methyl-2-thienyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methylthiophene-2-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.