Description

2-(5-Chloro-4-Methylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1111095-98-7 is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: Versatile boronic ester for academic and industrial R&D in organic synthesis and methodology development.
• Ligand & Catalyst Preparation: Precursor for synthesizing specialized ligands and catalysts used in homogeneous catalysis.
• Polymer Chemistry: Monomer for introducing functional thiophene units into polymer backbones for specialized coatings and conductive polymers.

Basic Information

Product Name	2-(5-Chloro-4-Methylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1111095-98-7
Molecular Formula	C11H16BClO2S
Molecular Weight	258.57 g/mol
Synonyms	5-Chloro-4-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 2-(5-Chloro-4-methyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-4-methylthiophene-2-boronic acid pinacol ester; (5-Chloro-4-methylthiophen-2-yl)boronic acid pinacol ester; Pinacol (5-chloro-4-methylthiophen-2-yl)boronate; CAS 1111095-98-7
EINECS	Contact for details

Quality Control

Our production of 2-(5-Chloro-4-Methylthiophen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed via NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.