Description

1-Fluorocyclopropane-1-Sulfonamide is a high-value fluorinated sulfonamide building block of significant interest in modern synthetic chemistry. Its unique structure, featuring a strained cyclopropane ring functionalized with both fluorine and a sulfonamide group, makes it a versatile precursor for the development of novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-modifying properties of the fluorine atom and sulfonamide moiety.
• Chemical Biology Probe: Serves as a valuable scaffold for creating molecular probes to study biological pathways and protein function.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers and advanced materials with tailored properties.
• Sulfonylating Agent: Acts as a reagent for introducing the sulfonamide functional group into other molecules under controlled conditions.
• Academic & Contract Research: Employed in universities and CROs for methodological development and exploration of new fluorination and cyclopropanation reactions.

Basic Information

Product Name	1-Fluorocyclopropane-1-Sulfonamide
CAS No.	1108658-19-0
Molecular Formula	C3H6FNO2S
Molecular Weight	139.15 g/mol
Synonyms	1-Fluoro-1-sulfamoylcyclopropane; Cyclopropanesulfonamide, 1-fluoro-; 1-Fluorocyclopropanesulfonamide; 1-Fluoro-cyclopropane-1-sulfonic acid amide; 1-Fluoro-1-(aminosulfonyl)cyclopropane; 1-Fluorocyclopropane-1-sulfonic acid amide; 1-Fluoro-cyclopropanesulfonamide
EINECS	Contact for details

Quality Control

Our 1-Fluorocyclopropane-1-Sulfonamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data including HPLC, NMR, and MS to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.