Description

1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzimidazole is a high-value, functionalized benzimidazole derivative containing a pinacol boronate ester group, making it a crucial building block in modern synthetic chemistry. This compound is specifically engineered for applications requiring precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental to pharmaceutical and advanced material development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the benzimidazole pharmacophore.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, essential for creating biaryl structures in complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a valuable tool compound for bioconjugation and the development of chemical probes.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and exploring new synthetic pathways.

Basic Information

Product Name	1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzimidazole
CAS No.	1107627-02-0
Molecular Formula	C14H19BN2O2
Molecular Weight	258.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-benzimidazole; 1-Methyl-5-(pinacolboryl)-1H-benzimidazole; 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole; 1-Methyl-5-(pinacolatoboryl)-1H-benzimidazole; 5-(Pinacolboron)-1-methylbenzimidazole; 1-Methyl-5-(pinacol boronate)benzimidazole; 1-Methyl-5-benzimidazole pinacol boronic ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzimidazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.