Description

1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-2-Yl)Ethanone is a high-value, furan-based boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional organic molecules. The CAS number for this compound is 1107580-77-7.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed as a monomer or building block for creating conjugated polymers and organic electronic materials for OLEDs and sensors.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & Industrial R&D: Serves as a versatile reagent in medicinal chemistry and process chemistry for exploring new synthetic pathways.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-2-Yl)Ethanone
CAS No.	1107580-77-7
Molecular Formula	C₁₂H₁₉BO₄
Molecular Weight	238.09 g/mol
Synonyms	2-Acetyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan; 1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-furanyl]ethanone; 5-Acetyl-2-furylboronic acid pinacol ester; 2-Furylboronic acid, 5-acetyl-, pinacol ester; (5-Acetyl-2-furanyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furan-2-Yl)Ethanone is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and production use. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, keep the container under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability. The compound is moisture-sensitive; ensure the container is sealed properly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.