Description

2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Ylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for enabling efficient cross-coupling reactions, particularly in the construction of complex heterocyclic scaffolds. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing benzoxazole motifs.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Probe Development: Useful for creating molecular probes and labeled compounds for biochemical research.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Ylboronic Acid Pinacol Ester
CAS No.	1105710-32-4
Molecular Formula	C₁₄H₁₈BNO₄
Molecular Weight	275.11 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrobenzo[d]oxazol-2-one; 2-Oxo-2,3-dihydrobenzo[d]oxazole-6-boronic acid pinacol ester; Benzo[d]oxazol-2(3H)-one, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 6-(Pinacolatoboryl)-2,3-dihydrobenzo[d]oxazol-2-one; 2,3-Dihydro-2-oxobenzo[d]oxazole-6-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.