Description

6-Isopropylpyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic light-emitting diodes (OLEDs).
• Chemical Biology & Medicinal Chemistry: Facilitates the creation of compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules at various scales.

Basic Information

Product Name	6-Isopropylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1105665-37-9
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	(6-Isopropylpyridin-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-isopropylpyridine; 6-Isopropyl-3-pyridineboronic acid pinacol ester; 6-Isopropyl-3-pyridinylboronic acid pinacol ester; 6-Isopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-(6-isopropyl-3-pyridinyl)-, 1,1-dimethylethyl ester; 1105665-37-9 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Isopropylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.