Description

4-[3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propyl]-Morpholine is a high-value, synthetically versatile boronic ester derivative. This compound is a critical building block in modern organic synthesis, particularly valued for its role in cross-coupling reactions. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries to construct complex molecular architectures. Its unique structure combines a morpholine moiety with a protected boronic acid group, offering specific reactivity and solubility profiles.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-morpholine motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity tags for studying biological systems and protein interactions.
• Ligand & Catalyst Development: Acts as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring this specific boronic ester.

Basic Information

Item	Details
Product Name	4-[3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propyl]-Morpholine
CAS No.	1105664-48-9
Molecular Formula	C19H30BNO3
Molecular Weight	331.26 g/mol
Synonyms	4-(3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propyl)morpholine; 2-(4-(3-Morpholinopropyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-[3-(4-morpholinyl)propyl]phenyl]-1,3,2-dioxaborolane; 4-(3-(4-(Pinacolatoboryl)phenyl)propyl)morpholine; 4-(3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propyl)morpholine; 1105664-48-9; Arylboronic ester morpholine derivative
EINECS	Contact for details

Quality Control

Our 4-[3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Propyl]-Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.