Description

Benzene-1,4-Diboronic Acid Mono-Mida Ester is a high-value, bifunctional organoboron building block where one boronic acid moiety is protected as a stable N-methyliminodiacetic acid (MIDA) ester. This compound matters because it enables sophisticated, sequential Suzuki-Miyaura cross-coupling reactions, offering chemists precise control over complex molecule assembly, particularly in the synthesis of conjugated systems and dendrimers. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing advanced organic electronic materials and bioactive compound intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the sequential synthesis of complex biaryl and heterobiaryl structures in drug discovery and development.
• Organic Electronic Materials: Used in the controlled synthesis of conjugated polymers, oligomers, and small molecules for OLEDs, OFETs, and organic photovoltaics.
• Agrochemical Synthesis: Enables the construction of novel, active ingredient scaffolds with specific spatial configurations.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated bidentate or polydentate ligands.
• Dendrimer and Polymer Chemistry: Facilitates controlled, iterative coupling reactions to build well-defined macromolecular architectures.
• Chemical Biology Probes: Utilized in synthesizing tagged molecules or bioconjugates for imaging and diagnostic applications.
• Academic & Industrial R&D: A versatile tool for methodological development in cross-coupling and new material discovery.

Basic Information

Product Name	Benzene-1,4-Diboronic Acid Mono-Mida Ester
CAS No.	1104665-01-1
Molecular Formula	C13H17B2NO6
Molecular Weight	320.90 g/mol
Synonyms	1,4-Phenylenebis(boronic acid) mono-MIDA ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylboronic acid MIDA ester; 1,4-Benzenediboronic acid, mono(N-methyliminodiacetate) ester; p-Phenylenediboronic acid mono-MIDA ester; B,B'-(1,4-Phenylene)bis(boronic acid) mono-MIDA ester; 4-(MIDA-boronate)phenylboronic acid; (4-Boronophenyl)boronic acid MIDA ester
EINECS	Contact for details

Quality Control

Our Benzene-1,4-Diboronic Acid Mono-Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.