Description

Cyclohexylboronic Acid Mida Ester CAS NO 1104637-39-9 is a protected boronic acid derivative, specifically the N-methyliminodiacetic acid (MIDA) ester of cyclohexylboronic acid. This compound is a crucial building block in modern synthetic chemistry, offering enhanced stability and handling characteristics compared to its free boronic acid counterpart. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the controlled synthesis of complex molecules via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boron reagent for the controlled introduction of the cyclohexyl group into biaryl and other complex structures.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating chiral centers and lipophilic fragments.
• Agrochemical Product Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific cyclohexyl-based architectures.
• Material Science Research: Acts as a precursor for creating organic electronic materials, ligands for catalysis, and novel polymers.
• Iterative Cross-Coupling (ICC): Ideal for automated, multi-step synthesis platforms due to the MIDA group's stability under various reaction conditions and its selective deprotection profile.
• Chemical Biology & Probe Development: Utilized to synthesize molecular probes and labeled compounds for biological target identification and mechanism-of-action studies.

Basic Information

Product Name	Cyclohexylboronic Acid Mida Ester
CAS No.	1104637-39-9
Molecular Formula	C13H22BNO4
Molecular Weight	267.13 g/mol
Synonyms	Cyclohexyl MIDA Boronate; Cyclohexylboronic Acid N-Methyliminodiacetic Acid Ester; Cyclohexyl-B(MIDA); N-Methyliminodiacetic Acid Cyclohexylboronate; (Cyclohexylboronyl)-N-methyliminodiacetic Acid; B-Cyclohexyl-N-methyliminodiacetic acid boronate; Cyclohexyl MIDA Ester; Cyclohexylboronic Acid MIDA Ester
EINECS	Contact for details

Quality Control

Our Cyclohexylboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC for purity assessment, and FT-IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.