Description

Cyclopropylboronic Acid Methyliminodiacetic Acid Anhydride is a specialized bifunctional reagent designed for advanced synthetic chemistry. This compound is critical for enabling efficient and selective cross-coupling reactions, particularly in the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) containing cyclopropane rings, which are valuable motifs in drug discovery.
• Suzuki-Miyaura Cross-Coupling: Serves as a cyclopropylboron source for palladium-catalyzed cross-coupling reactions with aryl or vinyl halides.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate cyclopropyl groups for enhanced biological activity.
• Material Science Research: Employed in the creation of advanced organic materials and ligands for catalysis.
• Process Chemistry: Facilitates scalable, efficient routes for the production of complex organic molecules in pilot plant and manufacturing settings.
• Academic & Contract Research: A valuable tool for methodological development and the exploration of new chemical space in academic and CRO laboratories.

Basic Information

Product Name	Cyclopropylboronic Acid Methyliminodiacetic Acid Anhydride
CAS No.	1104637-36-6
Molecular Formula	C9H14BNO5
Molecular Weight	227.03 g/mol
Synonyms	MIDA Cyclopropylboronate; Cyclopropylboronic Acid MIDA Ester; Cyclopropyl-MIDA-boronate; (Cyclopropylboronyl)methyliminodiacetic Acid Anhydride; N-Methyliminodiacetic Acid (Cyclopropylboronic Acid) Anhydride; B-Cyclopropyl-N-methyliminodiacetic Acid Boronate; CyclopropylB(MIDA)
EINECS	Contact for details

Quality Control

Our Cyclopropylboronic Acid Methyliminodiacetic Acid Anhydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive cross-coupling applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our production facilities are designed to meet the stringent requirements of cGMP for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.