Description

4-Pyridineboronic Acid Mida Ester is a protected boronic acid derivative, specifically the N-methyliminodiacetic acid (MIDA) ester of 4-pyridineboronic acid. This compound is a crucial building block in modern synthetic chemistry, offering enhanced stability and controlled reactivity for cross-coupling reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the synthesis of complex heterocyclic compounds, agrochemicals, and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, enabling the synthesis of biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Serves as a protected boronic acid synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyridine motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science Research: Employed in the creation of organic ligands for catalysis, metal-organic frameworks (MOFs), and functional polymers.
• Library Synthesis for Drug Discovery: Facilitates the rapid and reliable generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	4-Pyridineboronic Acid Mida Ester
CAS No.	1104636-72-7
Molecular Formula	C₁₀H₁₁BN₂O₄
Molecular Weight	234.02 g/mol
Synonyms	4-Pyridinylboronic Acid MIDA Ester; (4-Pyridinyl)-N-methyliminodiacetic acid Boronate; 4-Pyridineboronic Acid N-Methyliminodiacetic Acid (MIDA) Ester; 4-Pyridylboronic Acid MIDA Ester; B-(4-Pyridinyl)-N-methyliminodiacetic acid Boronate; 1104636-72-7; 4-Py-BMIDA
EINECS	Contact for details

Quality Control

Our 4-Pyridineboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.