Description

5-Acetylpyridine-3-Boronic Acid Pinacol Ester is a high-purity, functionalized boronic ester building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily needed by pharmaceutical R&D teams, agrochemical researchers, and advanced material scientists for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of advanced polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Enables the introduction of the 5-acetylpyridine moiety into complex molecules via palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Used to prepare novel bidentate or tridentate ligands for catalysis and coordination chemistry.
• Academic & Contract Research: A valuable reagent for methodology development and discovery chemistry in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Acetylpyridine-3-Boronic Acid Pinacol Ester
CAS No.	1103862-13-0
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	(5-Acetylpyridin-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-acetylpyridine; 5-Acetyl-3-pyridineboronic acid pinacol ester; 5-Acetyl-3-pyridinylboronic acid pinacol ester; Pinacol (5-acetylpyridin-3-yl)boronate; 5-Acetyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Acetylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.