Description

5-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in enabling the efficient and selective construction of complex heterocyclic compounds, which are critical scaffolds in advanced material and pharmaceutical research. This product is specifically designed for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile organoboron reagent for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone of medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate substituted pyridine structures.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: A precursor for developing organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	5-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1101205-22-4
Molecular Formula	C13H20BNO2
Molecular Weight	233.11 g/mol
Synonyms	2-(5-Methylpyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methyl-2-pyridineboronic acid pinacol ester; 2-(5-Methyl-2-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methylpyridine-2-boronic acid neopentyl glycol ester (common alternative); 2-(5-Methylpyridin-2-yl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; Pinacol (5-methylpyridin-2-yl)boronate; 5-Methyl-2-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-Methylpyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process chemistry. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project needs, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: 98-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.