Description

1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-1,2,3-Triazole is a high-value, functionalized boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who are developing new active ingredients, ligands, and functional polymers. The precise functionalization offered by this reagent is key to advancing drug discovery programs and creating novel advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing triazole and biaryl motifs prevalent in oncology, antiviral, and anti-inflammatory therapies.
• Agrochemical Research: Used in constructing complex molecules for next-generation herbicides, fungicides, and insecticides, leveraging the Suzuki coupling for efficient scaffold diversification.
• Materials Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, conductive polymers, and metal-organic frameworks (MOFs) where precise molecular architecture is required.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized N-heterocyclic carbene (NHC) ligands and other coordinating agents used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in click chemistry and bioconjugation strategies to create molecular probes for studying biological processes and diagnostics.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Item	Details
Product Name	1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-1,2,3-Triazole
CAS No.	1101174-00-8
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	4-(1H-1,2,3-Triazol-1-yl)phenylboronic acid pinacol ester; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-1,2,3-triazole; 1H-1,2,3-Triazole, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 4-(1,2,3-Triazol-1-yl)benzeneboronic acid pinacol ester; 1-(4-Pinacolatoboronphenyl)-1H-1,2,3-triazole; 1-(4-Boronophenyl)-1H-1,2,3-triazole pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-1,2,3-Triazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR (1H & 13C) for structural confirmation, and mass spectrometry for identity verification. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal quality standards and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and handled under inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.