Description

3-Benzyloxy-5-Chlorophenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzyl-protected aniline structure. This compound is critical for enabling complex synthetic pathways in medicinal chemistry, offering a versatile building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transport or host materials for advanced display technologies.
• Ligand and Catalyst Development: Functions as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Employed in the synthesis of specialized chromophores and high-performance pigments.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name	3-Benzyloxy-5-Chlorophenylamine
CAS No.	1100752-67-7
Molecular Formula	C₁₃H₁₂ClNO
Molecular Weight	233.69 g/mol
Synonyms	5-Chloro-3-(phenylmethoxy)aniline; 3-(Benzyloxy)-5-chloroaniline; 1-Benzyloxy-3-chloro-5-aminobenzene; Benzenamine, 5-chloro-3-(phenylmethoxy)-; 3-Amino-5-chlorophenyl benzyl ether; 5-Chloro-3-benzyloxyaniline; (3-Amino-5-chlorophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-5-Chlorophenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.