Description

(3-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid is a specialized boronic acid derivative featuring a pyrrolidine-substituted benzyl group. This compound is a valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions, due to its unique structural motif. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, especially those targeting central nervous system (CNS) disorders, via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides by enabling the introduction of complex aromatic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of advanced organic materials and polymers.
• Chemical Biology Probes: Employed in the creation of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Ligand Development: The pyrrolidine moiety can be exploited in the design of novel catalysts and chiral ligands for asymmetric synthesis.

Basic Information

Product Name	(3-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid
CAS No.	1100095-09-7
Molecular Formula	C11H16BNO2
Molecular Weight	205.07 g/mol
Synonyms	[3-(Pyrrolidin-1-ylmethyl)phenyl]boronic acid; 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]pyrrolidine (protected form); 3-(Pyrrolidin-1-ylmethyl)benzeneboronic acid; (3-(Pyrrolidin-1-ylmethyl)phenyl)boronic acid; Boronic acid, B-[3-(1-pyrrolidinylmethyl)phenyl]-; CAS 1100095-09-7
EINECS	Contact for details

Quality Control

Our (3-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid is manufactured under strict quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.