Description

1,3-Dichloro-2-(2,2,2-trifluoroethyl)benzene is a high-purity, halogenated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine and chlorine atoms is crucial for modulating biological activity and physicochemical properties. Industries that require precision intermediates for research and production, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the dichloro-trifluoroethyl moiety can contribute to pesticidal activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Precursor: Acts as a specialized intermediate in the production of fluorinated compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D laboratories for constructing complex aromatic systems, studying reaction mechanisms involving halogenated aromatics, and developing new synthetic methodologies.
• Polymer Modifier: Can be utilized to introduce halogenated aromatic units into polymer chains, potentially altering thermal stability, flame retardancy, or solubility characteristics of advanced polymeric materials.

Basic Information

Product Name	1,3-Dichloro-2-(2,2,2-trifluoroethyl)benzene
CAS No.	1099598-25-0
Molecular Formula	C8H5Cl2F3
Molecular Weight	229.03 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)-1,3-dichlorobenzene; 1,3-Dichloro-2-(trifluoroethyl)benzene; Benzene, 1,3-dichloro-2-(2,2,2-trifluoroethyl)-; 1,3-Dichloro-2-(2,2,2-trifluoroethyl)benzol; (2,2,2-Trifluoroethyl)-1,3-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-2-(2,2,2-trifluoroethyl)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), identity (by IR/GC-MS), and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Density	~1.5 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.