Description

1-Bromo-3-(2,2-Difluoropropyl)Benzene is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its unique molecular structure, which incorporates both bromine and difluoropropyl functional groups, enabling precise chemical modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the difluoropropyl moiety can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays, leveraging its benzene core for molecular engineering.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Research: An important reagent for studying the effects of fluorine introduction on the physicochemical properties of organic molecules.
• Polymer Modification: Employed to introduce functional side chains into polymer backbones to alter material properties like solubility and thermal stability.

Basic Information

Product Name	1-Bromo-3-(2,2-Difluoropropyl)Benzene
CAS No.	1099598-19-2
Molecular Formula	C9H9BrF2
Molecular Weight	235.07 g/mol
Synonyms	3-(2,2-Difluoropropyl)-1-bromobenzene; 1-Bromo-3-(2,2-difluoropropyl)benzene; m-(2,2-Difluoropropyl)bromobenzene; Benzene, 1-bromo-3-(2,2-difluoropropyl)-; (2,2-Difluoropropyl)benzene, 3-bromo-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(2,2-Difluoropropyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.