Description

(2-Formyl-4,5-Dimethoxyphenyl)Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative featuring both a formyl group and a protected boronic acid moiety. This compound is a critical synthetic intermediate, prized for its dual reactivity which enables efficient cross-coupling and subsequent functionalization in a single molecular framework. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as academic researchers, for constructing complex molecules via Suzuki-Miyaura coupling and other advanced organic synthesis protocols.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its structural complexity.
• Material Science Research: Serves as a precursor for functionalized organic materials, including ligands for catalysts and monomers for specialty polymers.
• Suzuki-Miyaura Cross-Coupling: The pinacol-protected boronic ester group facilitates efficient palladium-catalyzed cross-coupling reactions with aryl/vinyl halides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and sensors due to its reactive aldehyde and boronate functionalities.
• Academic & Contract Research: A valuable reagent for methodology development and complex natural product synthesis in academic and CRO laboratories.

Basic Information

Item	Detail
Product Name	(2-Formyl-4,5-Dimethoxyphenyl)Boronic Acid Pinacol Ester
CAS No.	1098755-60-2
Molecular Formula	C15H21BO5
Molecular Weight	292.14 g/mol
Synonyms	4,5-Dimethoxy-2-formylphenylboronic acid pinacol ester; 2-Formyl-4,5-dimethoxybenzeneboronic acid pinacol ester; (4,5-Dimethoxy-2-formylphenyl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5-dimethoxybenzaldehyde; PINACOL (2-FORMYL-4,5-DIMETHOXYPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Every batch of (2-Formyl-4,5-Dimethoxyphenyl)Boronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to ensure identity and consistency. A Certificate of Analysis (COA) is available for each lot, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.