Description

1,2-Bis(1,1-Dimethylethyl) 4-Oxo-1,2-Pyrrolidinedicarboxylate is a high-purity, protected pyrrolidine derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex nitrogen-containing heterocycles, enabling the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of N-protected proline analogs and other pharmacologically active pyrrolidine-based compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate a pyrrolidine scaffold.
• Peptidomimetics Research: Serves as a protected precursor for introducing constrained proline-like structures into peptide analogs to enhance stability and biological activity.
• Asymmetric Catalysis: Potential precursor for chiral ligands or organocatalysts used in stereoselective synthesis.
• Material Science: Intermediate in the development of specialty polymers and functional organic materials with tailored properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	1,2-Bis(1,1-Dimethylethyl) 4-Oxo-1,2-Pyrrolidinedicarboxylate
CAS No.	1098652-11-9
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	Di-tert-butyl 4-oxopyrrolidine-1,2-dicarboxylate; 1,2-Di-tert-butyl 4-oxo-1,2-pyrrolidinedicarboxylate; 4-Oxopyrrolidine-1,2-dicarboxylic acid di-tert-butyl ester; 1-Boc-4-oxo-D-proline tert-butyl ester (common naming); N-Boc-4-oxoproline OtBu ester; N-tert-Butoxycarbonyl-4-oxoproline tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1,2-Bis(1,1-Dimethylethyl) 4-Oxo-1,2-Pyrrolidinedicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.