Description

3-(3,4-Difluorophenyl)Propanamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorophenyl moiety is prized for its ability to modulate biological activity and improve metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific fluorinated pharmacophore into their molecular targets.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly in central nervous system (CNS) and oncology research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where fluorination enhances lipophilicity and target binding.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced materials with unique electronic or surface properties.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic & Industrial R&D: Utilized in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-(3,4-Difluorophenyl)Propanamide
CAS No.	1098350-17-4
Molecular Formula	C9H9F2NO
Molecular Weight	185.17 g/mol
Synonyms	3-(3,4-Difluorophenyl)propanamide; 3,4-Difluorohydrocinnamamide; 3-(3,4-Difluorophenyl)propionamide; Propanamide, 3-(3,4-difluorophenyl)-; 1098350-17-4; 3,4-Difluoro-β-phenylpropionamide; 3-(3,4-Difluorophenyl)propaneamide
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorophenyl)Propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates, including those under development for regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.