Description

1-(Trifluoromethyl)Cyclobutan-1-Ol is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclobutane ring and a trifluoromethyl alcohol group, makes it a valuable intermediate for introducing steric bulk and fluorine atoms into target molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with tailored surface properties and chemical resistance.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the properties of fluorinated alicyclic compounds.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclobutan-1-Ol
CAS No.	1098183-73-3
Molecular Formula	C5H7F3O
Molecular Weight	140.10 g/mol
Synonyms	α-(Trifluoromethyl)cyclobutylmethanol; (Trifluoromethyl)cyclobutanol; 1-Hydroxy-1-(trifluoromethyl)cyclobutane; Cyclobutanol, 1-(trifluoromethyl)-; 1-Trifluoromethylcyclobutan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)Cyclobutan-1-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.