Description

1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine is a high-value fluorinated aromatic amine building block, distinguished by its unique trifluoromethyl and fluorine substituents which impart significant electronic and steric properties. This compound is essential for research and development in advanced organic synthesis, where it serves as a critical precursor for creating novel molecules with tailored functionalities. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in drug discovery, crop protection, and specialty polymer development.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and solubility.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostic applications.

Basic Information

Product Name	1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine
CAS No.	1098068-92-8
Molecular Formula	C9H7F4N
Molecular Weight	205.15 g/mol
Synonyms	1-(4-Fluoro-3-(trifluoromethyl)phenyl)ethanamine; α-Methyl-4-fluoro-3-(trifluoromethyl)benzylamine; 1-(4-Fluoro-3-trifluoromethylphenyl)ethylamine; 4-Fluoro-α-methyl-3-(trifluoromethyl)benzenemethanamine; 1-[4-Fluoro-3-(trifluoromethyl)phenyl]ethanamine; 4-Fluoro-3-trifluoromethylphenethylamine, α-methyl derivative; (4-Fluoro-3-trifluoromethylphenyl)ethylamine
EINECS	Contact for details

Quality Control

Our 1-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), our technical team is available to discuss tailored quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.