Description

B-(1,2,3,4-Tetrahydro-7-Isoquinolinyl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals. Its specific isoquinoline-based structure makes it valuable for creating novel heterocyclic compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides through cross-coupling methodologies.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as organic semiconductors and ligands for catalysis.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tools for studying biological processes and enzyme functions.
• Academic & Industrial R&D: A fundamental reagent for synthetic organic chemists in both university laboratories and corporate R&D centers exploring new chemical spaces.

Basic Information

Product Name	B-(1,2,3,4-Tetrahydro-7-Isoquinolinyl)Boronic Acid
CAS No.	1096359-11-3
Molecular Formula	C9H12BNO2
Molecular Weight	177.01 g/mol
Synonyms	(1,2,3,4-Tetrahydroisoquinolin-7-yl)boronic Acid; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroisoquinoline; B-(1,2,3,4-Tetrahydro-7-isoquinolinyl)boronic Acid; 1,2,3,4-Tetrahydro-7-isoquinolineboronic Acid; 7-Borono-1,2,3,4-tetrahydroisoquinoline; THIQ-7-Boronic Acid; 1096359-11-3; 7-(Tetrahydroisoquinolinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our B-(1,2,3,4-Tetrahydro-7-Isoquinolinyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C) to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.