Description

1-(4-(Trifluoromethyl)Phenyl)Pyrrolidin-3-One CAS NO 1096301-15-3 is a high-purity, advanced pharmaceutical intermediate featuring a pyrrolidinone core substituted with a trifluoromethylphenyl group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for functionalized molecules in the development of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-(Trifluoromethyl)Phenyl)Pyrrolidin-3-One
CAS No.	1096301-15-3
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-pyrrolidinone; 3-Pyrrolidinone, 1-[4-(trifluoromethyl)phenyl]-; 1-(4-Trifluoromethylphenyl)pyrrolidin-3-one; 1-(p-Trifluoromethylphenyl)-3-pyrrolidinone; 1096301-15-3; 1-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-one
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethyl)Phenyl)Pyrrolidin-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.