Description

n-Methyl 2-Benzyloxy-5-Fluorobenzylamine is a high-purity, specialized organic building block featuring a benzyl-protected phenolic ether and a primary amine functionality. This compound is critical for pharmaceutical research and development, serving as a versatile intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce specific fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorinated aromatic structure enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein interactions.
• Advanced Material Precursor: Utilized in the research of organic semiconductors and liquid crystals due to its rigid, substituted benzene core.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	n-Methyl 2-Benzyloxy-5-Fluorobenzylamine
CAS No.	1096291-17-6
Molecular Formula	C15H16FNO
Molecular Weight	245.29 g/mol
Synonyms	1-(Benzyloxy)-2-[(methylamino)methyl]-4-fluorobenzene; 2-(Benzyloxy)-5-fluoro-N-methylbenzylamine; 5-Fluoro-2-(benzyloxy)-N-methylbenzenemethanamine; Benzenemethanamine, 5-fluoro-2-(phenylmethoxy)-N-methyl-; N-Methyl-1-(phenylmethoxy)-4-fluoro-2-(aminomethyl)benzene; N-Methyl-2-benzyloxy-5-fluorobenzylamine; (2-(Benzyloxy)-5-fluorophenyl)-N-methylmethanamine
EINECS	Contact for details

Quality Control

Our n-Methyl 2-Benzyloxy-5-Fluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates, including those under development for regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.