Description

4-(2-Methylphenyl)-2,3-Dihydro-1,3-Thiazol-2-One is a high-value, specialized heterocyclic organic compound featuring a thiazolone core fused with an o-tolyl substituent. This structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in research for creating new active ingredients for crop protection products.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the thiazolone moiety into larger molecular architectures.
• Biochemical Probe Synthesis: Utilized in the development of chemical probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	4-(2-Methylphenyl)-2,3-Dihydro-1,3-Thiazol-2-One
CAS No.	1095231-46-1
Molecular Formula	C10H9NOS
Molecular Weight	191.25 g/mol
Synonyms	4-(o-Tolyl)-2,3-dihydro-1,3-thiazol-2-one; 2,3-Dihydro-4-(2-methylphenyl)-2-thiazolone; 4-(2-Methylphenyl)-2-thiazolidinone; 2-Thiazolidinone, 4-(2-methylphenyl)-; 4-(2-Methylphenyl)thiazolidin-2-one; 1095231-46-1
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Every batch of 4-(2-Methylphenyl)-2,3-Dihydro-1,3-Thiazol-2-One is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.