Description

4-Formyl-3-(Trifluoromethyl)-1-Methyl-1H-Pyrazole is a high-value trifluoromethylated pyrazole derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a formyl group and a trifluoromethyl substituent, makes it indispensable for introducing these functional motifs into target molecules, thereby modulating their physicochemical and biological properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Employed in the creation of novel organic ligands for catalysis or as a monomer for specialty polymers with unique electronic properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	4-Formyl-3-(Trifluoromethyl)-1-Methyl-1H-Pyrazole
CAS No.	1094484-55-5
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxaldehyde; 3-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde; 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxaldehyde; 4-Formyl-1-methyl-3-(trifluoromethyl)pyrazole; 1-Methyl-3-(trifluoromethyl)-4-pyrazolecarboxaldehyde; 3-Trifluoromethyl-1-methyl-4-formylpyrazole; 1-Methyl-3-trifluoromethylpyrazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Formyl-3-(Trifluoromethyl)-1-Methyl-1H-Pyrazole is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.