Description

2-(5-Chlorothiophen-2-Yl)-1,3-Thiazole-4-Carboxylic Acid is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry where its unique fused thiophene-thiazole core is leveraged for developing novel active ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating new chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used as a precursor for developing novel pesticides and herbicides with specific biological activity.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and liquid crystals due to its electron-rich heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in exploratory chemistry for creating novel compound libraries and investigating structure-activity relationships (SAR).

Basic Information

Product Name	2-(5-Chlorothiophen-2-Yl)-1,3-Thiazole-4-Carboxylic Acid
CAS No.	1094355-54-0
Molecular Formula	C8H4ClNO2S2
Molecular Weight	245.71 g/mol
Synonyms	5-Chloro-2-thienyl-4-thiazolecarboxylic Acid; 2-(5-Chloro-2-thienyl)-1,3-thiazole-4-carboxylic Acid; 4-Thiazolecarboxylic acid, 2-(5-chloro-2-thienyl)-; 2-(5-Chlorothiophen-2-yl)thiazole-4-carboxylic acid; 2-(5-Chloro-2-thienyl)-4-carboxythiazole; 1094355-54-0; 2-(5-Chlorothien-2-yl)-1,3-thiazol-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(5-Chlorothiophen-2-Yl)-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided and available upon request, supporting compliance with cGMP and other relevant quality guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its chemical nature as a strong acid/organic solvent-compatible compound, ensure proper segregation from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.