Description

1-(1-Bromoethyl)-2,4-Difluorobenzene is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique reactivity, serving as a critical intermediate in the synthesis of complex molecules where the introduction of a bromoethyl and difluoro-substituted phenyl group is required. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in advanced electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromoethyl moiety acts as an effective handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to create complex biaryl structures.
• Polymer Modification: Incorporated as a functional monomer or chain-transfer agent to introduce specific aromatic and halogenated properties into specialty polymers.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-(1-Bromoethyl)-2,4-Difluorobenzene
CAS No.	1094272-78-2
Molecular Formula	C8H7BrF2
Molecular Weight	221.04 g/mol
Synonyms	1-Bromo-1-(2,4-difluorophenyl)ethane; (1-Bromoethyl)-2,4-difluorobenzene; 2,4-Difluoro-α-bromoethylbenzene; α-Bromo-2,4-difluoroethylbenzene; 1-(2,4-Difluorophenyl)-1-bromoethane; (2,4-Difluorophenyl)methyl bromide, α-methyl-; 1094272-78-2
EINECS	Contact for details

Quality Control

Every batch of 1-(1-Bromoethyl)-2,4-Difluorobenzene is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are aligned with industry best practices for high-purity organic intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles via HPLC, GC, NMR, and IR is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.