Description

2-Acetamido-1,3,4-Tri-o-Acetyl-2,6-Dideoxy-6-Fluoro-D-Glucopyranose is a high-purity, fluorinated carbohydrate derivative serving as a critical advanced intermediate in modern synthetic chemistry. This compound is essential for researchers and manufacturers developing novel pharmaceuticals, particularly in the synthesis of fluorinated nucleoside analogs and other bioactive molecules. Its primary value lies in enabling precise structural modifications to enhance drug potency, metabolic stability, and bioavailability. Key industries that rely on this specialized building block include pharmaceutical R&D, contract manufacturing organizations (CMOs), and academic research institutions focused on medicinal chemistry and glycoscience.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated antiviral and anticancer nucleoside drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce fluorine atoms into sugar moieties of lead compounds.
• Glycobiology & Glycochemistry: Serves as a protected, fluorinated monosaccharide precursor for constructing complex oligosaccharides and glycoconjugates.
• Probe & Diagnostic Agent Development: Utilized in creating 18F-labeled precursors for Positron Emission Tomography (PET) imaging agents.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for investigating fluorination effects on carbohydrate reactivity and conformation.

Basic Information

Product Name	2-Acetamido-1,3,4-Tri-o-Acetyl-2,6-Dideoxy-6-Fluoro-D-Glucopyranose
CAS No.	1094213-88-3
Molecular Formula	C14H20FNO8
Molecular Weight	349.31 g/mol
Synonyms	2-Acetamido-1,3,4-tri-O-acetyl-2,6-dideoxy-6-fluoro-D-glucopyranose; 6-Fluoro-2-acetamido-1,3,4-tri-O-acetyl-2,6-dideoxy-D-glucopyranose; N-Acetyl-6-fluoro-1,3,4-tri-O-acetyl-2,6-dideoxy-D-glucosamine; 2,6-Dideoxy-6-fluoro-2-acetamido-1,3,4-tri-O-acetyl-D-glucopyranose; Fluorinated D-Glucosamine Derivative; 6-Fluoro-D-glucosamine tetraacetate derivative
EINECS	Contact for details

Quality Control

Our 2-Acetamido-1,3,4-Tri-o-Acetyl-2,6-Dideoxy-6-Fluoro-D-Glucopyranose is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with complete analytical data are provided for each lot. We support compliance with cGMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.