Description

4-Fluorohexahydro-1H-Azepine Hydrochloride is a fluorinated azepane derivative, a valuable building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of novel pharmaceutical candidates, especially those targeting central nervous system (CNS) disorders. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug molecules, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated azepane scaffold.
• Chemical Biology Probes: Serves as a building block for creating tool compounds and probes to study biological pathways and protein function.
• Agrochemical Development: Potential intermediate in the research and synthesis of new active ingredients for crop protection.
• Academic Research: Utilized in universities and research institutes for methodological development in organic and fluorine chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	4-Fluorohexahydro-1H-Azepine Hydrochloride
CAS No.	1094073-73-0
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	4-Fluoroazepane hydrochloride; 4-Fluorohexahydro-1H-azepine HCl; 4-Fluoroazepan-1-ium chloride; 4-Fluoro-1-azacycloheptane hydrochloride; 4-Fluoroazepane HCl salt; 4-Fluoro-azepane hydrochloride; 4-Fluoro-1-azoniacycloheptane chloride
EINECS	Contact for details

Quality Control

Our 4-Fluorohexahydro-1H-Azepine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.