Description

2,3-Difluoro-4-Methoxypropiophenone is a high-value fluorinated aromatic ketone building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its difluoro-methoxy substitution pattern offers unique electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing industries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and charge-transport materials due to its electron-withdrawing characteristics.
• Chemical Research: A versatile building block for Suzuki, Heck, and other cross-coupling reactions in academic and industrial R&D laboratories.
• Fluorine Chemistry Studies: Used as a model compound for studying the effects of specific fluorine substitution patterns on molecular reactivity and conformation.

Basic Information

Product Name	2,3-Difluoro-4-Methoxypropiophenone
CAS No.	1093857-88-5
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	1-(2,3-Difluoro-4-methoxyphenyl)propan-1-one; 2,3-Difluoro-4-methoxypropiophenone; Propiophenone, 2,3-difluoro-4-methoxy-; 2,3-Difluoro-4-methoxy-1-propiophenone; 2',3'-Difluoro-4'-methoxypropiophenone; 1-Propanone, 1-(2,3-difluoro-4-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxypropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.