Description

3-(3-Benzyloxy-Propoxy)-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde is a high-value, advanced pharmaceutical intermediate featuring a benzaldehyde core functionalized with a benzyl-protected alkoxy chain and a pinacol boronate ester group. This compound matters as a critical building block in modern organic synthesis, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl or conjugated systems.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for palladium-catalyzed coupling with aryl or vinyl halides to form new C-C bonds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that contain complex aromatic structures.
• Material Science Research: Building block for creating organic electronic materials, such as OLEDs and conductive polymers, where defined conjugation is essential.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized boronate esters.

Basic Information

Product Name	3-(3-Benzyloxy-Propoxy)-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde
CAS No.	1093643-90-3
Molecular Formula	C23H29BO5
Molecular Weight	396.28 g/mol
Synonyms	2-Formyl-6-(3-(benzyloxy)propoxy)phenylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-[3-(phenylmethoxy)propoxy]benzaldehyde; Benzaldehyde, 3-[3-(benzyloxy)propoxy]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol [2-formyl-6-(3-benzyloxypropoxy)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 3-(3-Benzyloxy-Propoxy)-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.