Description

Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate is a high-value, multifunctional chemical building block that integrates a protected boronic ester with a pyrazole heterocycle and an ester functionality. This compound matters for its versatility in modern synthetic chemistry, enabling precise carbon-carbon bond formation and serving as a key precursor in complex molecule assembly. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrazole moiety for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in creating bioconjugates and molecular probes for diagnostic and biochemical research applications.
• Academic & Contract Research: A valuable reagent for methodology development and complex natural product synthesis in academic and CRO laboratory settings.

Basic Information

Item	Details
Product Name	Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate
CAS No.	1093307-33-5
Molecular Formula	C13H21BN2O4
Molecular Weight	280.13 g/mol
Synonyms	Methyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanoate; 1H-Pyrazole-1-propanoic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanoic acid methyl ester; Methyl 3-(4-(pinacolatoboryl)-1H-pyrazol-1-yl)propanoate; 4-Pinacolatoboryl-1H-pyrazole-1-propanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.